Viagra, also known by its generic name sildenafil, is a well-known medication used to treat erectile dysfunction (ED) in men. Since its introduction in 1998, Viagra has helped millions of men regain their sexual confidence and improve their intimate relationships. But have you ever wondered how this little blue pill actually works? In this article, we will explore the mechanism behind Viagra and its effects on the body.
- Viagra is classified as a phosphodiesterase type 5 (PDE5) inhibitor. It works by selectively targeting the enzyme PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the penis. During sexual arousal, the release of nitric oxide (NO) leads to the production of cGMP, which causes the smooth muscles in the penile arteries to relax. This relaxation allows increased blood flow into the penis, resulting in an erection.
- In men with erectile dysfunction, the enzyme PDE5 breaks down cGMP too quickly, leading to insufficient blood flow and difficulty in achieving or maintaining an erection. By inhibiting PDE5, Viagra helps to prolong the effects of cGMP, allowing the smooth muscles to stay relaxed and promoting a healthy blood flow to the penis.
- Viagra is quickly absorbed into the bloodstream after oral use. The peak concentration of the drug in the body occurs within one hour. It is important to note that Viagra does not cause spontaneous erections. Sexual stimulation is still necessary to activate the release of nitric oxide and trigger the natural erectile response.
- It is recommended to take Viagra approximately 30 minutes to one hour before sexual activity. The effects of Viagra can last for up to four to six hours, depending on the individual’s metabolism and dosage. It is important to follow the prescribed dosage instructions and not to exceed the recommended amount.
- It is worth mentioning that Viagra may not be effective for everyone. Factors such as underlying medical conditions, psychological factors, or individual response to the medication can influence its effectiveness. It is always advisable to consult with a healthcare professional before starting any medication, including Viagra, to ensure it is safe and appropriate for you.
Like any medication, Viagra Kamagra en Europe can have side effects, although they are generally mild and temporary. Headaches, flushing of the face, gastrointestinal upset, and stuffy nose are just some of the potential adverse effects. In rare cases, more severe side effects may occur, such as priapism (prolonged and painful erection), sudden vision or hearing loss, or allergic reactions. If you experience any unusual or severe symptoms, it is important to seek medical attention immediately.
